Is CBD Safe to Use with Other Medications?

December 04, 2020

Find out what medications CBD affects to continue feeling your best.

CBD is a chemical compound known as a cannabinoid and is derived from hemp. This plant-based nootropic has many health benefits and is beginning to gain more popularity. Even those little corner gas stations sell CBD capsules. Of course, high-quality CBD is probably better than the gas station variety, but the truth is this: more people are looking to CBD to help them with health issues. This can be beneficial to them, but certain concerns arise when using CBD with other medications also meant to target health issues. Read on to find out if CBD is safe to use with other medications.

What is CBD Typically Used For?

CBD has been gaining popularity as a sort of natural remedy for health issues. It can help with a variety of things—from anxiety to arthritis. Some common uses of CBD are to help with muscle and joint pain, athletic recovery, anxiety, and depression. A88CBD™ has developed products that contain high-quality CBD and all-natural ingredients to help with these common health issues. Try A88CBD™’s muscle salve for deep relief or their gummies for ultimate wellness.

Along with helping promote wellness and manage health issues, CBD has been proven to reduce seizures in adults and children. It can also potentially help with relief of cancer-related symptoms, acne reduction, heart health, and have neuroprotective properties. Two main ways to take it are by applying a topical (which is best for localized pain relief) or by taking an ingestible (best for stress and anxiety relief). With many wellness-related benefits, it is clear to see why people are turning to CBD products to help them feel their best.

How Does CBD Work in the Body?

Our bodies have an endocannabinoid system that CBD interacts with. The endocannabinoid system is an ubiquitous biological system in our bodies made up of receptors, enzymes, and endocannabinoids. This system helps regulate sleep, appetite, mood, immune responses, cell communication, and more. CBD is an endocannabinoid that will bind to the receptors for them in our body. Once they bind with these receptors is when the wellness magic happens, such as chronic pain relief and relaxation. According to research, CBD can also influence and interact with non-cannabinoid receptors. It is believed that CBD helps modulate the 5ht serotonin receptor, which can help treat psychotic disorders, and the TRPV1 receptor, which plays a role in pain and inflammation.

How Does CBD Interact with Other Medications?

Putting CBD and other medications together can have different effects. Because CBD interacts with receptors in our body, it can reduce or increase the effects of prescribed medications. These medications and CBD are broken down by the same liver enzymes. CBD inhibits some liver enzymes but induces others. When it inhibits enzymes, it could make the medication in your body break down slower than usual, which could increase the side effects. When CBD induces enzymes, certain medications could be broken down faster, thus becoming less effective. Here are some types of medications that are affected by CBD:

Blood Thinners

CBD and other plant cannabinoids can increase and prolong the effects of medications like warfarin, ibuprofen, and apixaban.


Because CBD has sedative properties, when combined with sedative medication, the effects can increase. This increased effect does not seem to directly impact the user negatively, but not enough research has been conducted to know.

Anti-Seizure Medication

CBD has been commonly used for its anti-epileptic benefits. But when taken with other seizure medicine, it can actually prohibit the medicine from working and even result in more aggressive seizures.

Chemotherapy Drugs

Chemotherapy drugs are highly important to those undergoing cancer treatment. This type of medication relies on the rate it is metabolized for its effectiveness. When taken with CBD, higher concentrations of the drug enters the bloodstream and leads to toxicity.

Talk to Your Doctor

Because there is still a lot of uncertainty surrounding the effects of CBD on drug-metabolizing enzymes, it is best to talk to your doctor about CBD and medication before using the two together. Your doctor will be able to give you the go-ahead or not, or they can adjust the dosage of medication so that it may still be effective while taken with CBD.

Latest posts